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Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives
Post-translational methylation of histone lysine or arginine residues plays important roles in gene regulation and other physiological processes. Aberrant histone methylation caused by a gene mutation, translocation, or overexpression can often lead to initiation of a disease such as cancer. Small m...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912745/ https://www.ncbi.nlm.nih.gov/pubmed/27316347 http://dx.doi.org/10.1186/s13045-016-0279-9 |