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In vivo enhancement of the MAGE-specific cellular immune response by a recombinant MAGE1-MAGE3-TBHSP70 tumor vaccine

BACKGROUND: Since cytotoxic T cell (CTL) response is the major cellular type in attacking tumor cells, most immunotherapy targets to manipulate the CTL response. Immunotherapies targeting melanoma-specific antigens (MAGEs), a group of tumor-specific shared antigen, have shown to be promising. Our pr...

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Detalles Bibliográficos
Autores principales: Junwei, Wang, Xiumin, Zhan, Jing, Ye, Shoujing, Yang, Zengshan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912753/
https://www.ncbi.nlm.nih.gov/pubmed/27330408
http://dx.doi.org/10.1186/s12935-016-0317-2