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The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states

BACKGROUND: The epithelial to mesenchymal transition (EMT) has been implicated in metastasis and therapy resistance of carcinomas and can endow cancer cells with cancer stem cell (CSC) properties. The ability to detect cancer cells that are undergoing or have completed EMT has typically relied on th...

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Detalles Bibliográficos
Autores principales: Toneff, M. J., Sreekumar, A., Tinnirello, A., Hollander, P. Den, Habib, S., Li, S., Ellis, M. J., Xin, L., Mani, S. A., Rosen, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912796/
https://www.ncbi.nlm.nih.gov/pubmed/27317311
http://dx.doi.org/10.1186/s12915-016-0269-y