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The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states
BACKGROUND: The epithelial to mesenchymal transition (EMT) has been implicated in metastasis and therapy resistance of carcinomas and can endow cancer cells with cancer stem cell (CSC) properties. The ability to detect cancer cells that are undergoing or have completed EMT has typically relied on th...
Autores principales: | Toneff, M. J., Sreekumar, A., Tinnirello, A., Hollander, P. Den, Habib, S., Li, S., Ellis, M. J., Xin, L., Mani, S. A., Rosen, J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912796/ https://www.ncbi.nlm.nih.gov/pubmed/27317311 http://dx.doi.org/10.1186/s12915-016-0269-y |
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