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Pathophysiology of Motor Dysfunction in Parkinson's Disease as the Rationale for Drug Treatment and Rehabilitation

Cardinal motor features of Parkinson's disease (PD) include bradykinesia, rest tremor, and rigidity, which appear in the early stages of the disease and largely depend on dopaminergic nigrostriatal denervation. Intermediate and advanced PD stages are characterized by motor fluctuations and dysk...

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Detalles Bibliográficos
Autores principales: Magrinelli, Francesca, Picelli, Alessandro, Tocco, Pierluigi, Federico, Angela, Roncari, Laura, Smania, Nicola, Zanette, Giampietro, Tamburin, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913065/
https://www.ncbi.nlm.nih.gov/pubmed/27366343
http://dx.doi.org/10.1155/2016/9832839