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Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update

Hepatic injury and subsequent hepatic failure due to both intentional and non-intentional overdose of acetaminophen (APAP) has affected patients for decades, and involves the cornerstone metabolic pathways which take place in the microsomes within hepatocytes. APAP hepatotoxicity remains a global is...

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Detalles Bibliográficos
Autores principales: Yoon, Eric, Babar, Arooj, Choudhary, Moaz, Kutner, Matthew, Pyrsopoulos, Nikolaos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913076/
https://www.ncbi.nlm.nih.gov/pubmed/27350943
http://dx.doi.org/10.14218/JCTH.2015.00052