In silico analysis of deleterious single nucleotide polymorphisms in human BUB1 mitotic checkpoint serine/threonine kinase B gene

One of the major challenges in the analysis of human genetic variation is to distinguish mutations that are functionally neutral from those that contribute to disease. BubR1 is a key protein mediating spindle-checkpoint activation that plays a role in the inhibition of the anaphase-promoting complex...

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Detalles Bibliográficos
Autores principales: Akhoundi, Fatemeh, Parvaneh, Nikpour, Modjtaba, Emadi-Baygi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913181/
https://www.ncbi.nlm.nih.gov/pubmed/27331020
http://dx.doi.org/10.1016/j.mgene.2016.05.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913181/
https://www.ncbi.nlm.nih.gov/pubmed/27331020
http://dx.doi.org/10.1016/j.mgene.2016.05.002

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