Cargando…

CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia

In addition to antiplatelet autoantibodies, CD8(+) cytotoxic T lymphocytes (CTLs) play an important role in the increased platelet destruction in immune thrombocytopenia (ITP). Recent studies have highlighted that platelet desialylation leads to platelet clearance via hepatocyte asialoglycoprotein r...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Jihua, Liu, Xuena, Li, Xiaoqing, Zhang, Xu, Han, Panpan, Zhou, Hai, Shao, Linlin, Hou, Yu, Min, Yanan, Kong, Zhangyuan, Wang, Yawen, Wei, Yu, Liu, Xinguang, Ni, Heyu, Peng, Jun, Hou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913243/
https://www.ncbi.nlm.nih.gov/pubmed/27321376
http://dx.doi.org/10.1038/srep27445