Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue

Activation of inflammation in white adipose tissue (WAT), includes infiltration/expansion of WAT macrophages, contributes pathogenesis of obesity, insulin resistance, and metabolic syndrome. The inflammasome comprises an intracellular sensor (NLR), caspase-1 and the adaptor ASC. Inflammasome activat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmad, Faiyaz, Chung, Youn Wook, Tang, Yan, Hockman, Steven C., Liu, Shiwei, Khan, Yusuf, Huo, Kevin, Billings, Eric, Amar, Marcelo J., Remaley, Alan T., Manganiello, Vincent C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913246/
https://www.ncbi.nlm.nih.gov/pubmed/27321128
http://dx.doi.org/10.1038/srep28056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913246/
https://www.ncbi.nlm.nih.gov/pubmed/27321128
http://dx.doi.org/10.1038/srep28056

Ejemplares similares