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Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice

Presynaptic active zones play a pivotal role as synaptic vesicle release sites for synaptic transmission, but the molecular architecture of active zones in mammalian neuromuscular junctions (NMJs) at sub-diffraction limited resolution remains unknown. Bassoon and Piccolo are active zone specific cyt...

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Detalles Bibliográficos
Autores principales: Nishimune, Hiroshi, Badawi, Yomna, Mori, Shuuichi, Shigemoto, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913281/
https://www.ncbi.nlm.nih.gov/pubmed/27321892
http://dx.doi.org/10.1038/srep27935