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Ultrasensitive proteomic quantitation of cellular signaling by digitized nanoparticle-protein counting
Many important signaling and regulatory proteins are expressed at low abundance and are difficult to measure in single cells. We report a molecular imaging approach to quantitate protein levels by digitized, discrete counting of nanoparticle-tagged proteins. Digitized protein counting provides ultra...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913309/ https://www.ncbi.nlm.nih.gov/pubmed/27320899 http://dx.doi.org/10.1038/srep28163 |