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Knockdown of long noncoding RNA H19 sensitizes human glioma cells to temozolomide therapy
Temozolomide (TMZ) is commonly used in glioma chemotherapy. However, a great clinical challenge for TMZ is chemoresistance. H19 transcripts are recognized as long noncoding RNAs, which potentially interact with chromatin-modifying complexes to regulate gene expression via epigenetic changes. Our dat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913544/ https://www.ncbi.nlm.nih.gov/pubmed/27366087 http://dx.doi.org/10.2147/OTT.S96278 |