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Knockdown of long noncoding RNA H19 sensitizes human glioma cells to temozolomide therapy

Temozolomide (TMZ) is commonly used in glioma chemotherapy. However, a great clinical challenge for TMZ is chemoresistance. H19 transcripts are recognized as long noncoding RNAs, which potentially interact with chromatin-modifying complexes to regulate gene expression via epigenetic changes. Our dat...

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Detalles Bibliográficos
Autores principales: Jiang, Pengfei, Wang, Ping, Sun, Xiaoling, Yuan, Zhongshun, Zhan, Rucai, Ma, Xiangyu, Li, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913544/
https://www.ncbi.nlm.nih.gov/pubmed/27366087
http://dx.doi.org/10.2147/OTT.S96278

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