The Effect of the Canine ABCB1‐1Δ Mutation on Sedation after Intravenous Administration of Acepromazine

BACKGROUND: Dog breeds with the ABCB1‐1Δ mutation have substantially truncated nonfunctional P‐glycoprotein. Dogs homozygous for this mutation (mut/mut) are susceptible to the toxic adverse effects of ivermectin, loperamide, and vincristine. Anecdotal reports suggested ABCB1 mut/mut dogs showed incr...

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Detalles Bibliográficos
Autores principales: Deshpande, D., Hill, K.E., Mealey, K.L., Chambers, J.P., Gieseg, M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
SMALL ANIMAL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913601/
https://www.ncbi.nlm.nih.gov/pubmed/26822006
http://dx.doi.org/10.1111/jvim.13827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913601/
https://www.ncbi.nlm.nih.gov/pubmed/26822006
http://dx.doi.org/10.1111/jvim.13827

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