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Conditional gene deletion with DiCre demonstrates an essential role for CRK3 in L eishmania mexicana cell cycle regulation

Leishmania mexicana has a large family of cyclin‐dependent kinases (CDKs) that reflect the complex interplay between cell cycle and life cycle progression. Evidence from previous studies indicated that Cdc2‐related kinase 3 (CRK3) in complex with the cyclin CYC6 is a functional homologue of the majo...

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Detalles Bibliográficos
Autores principales: Duncan, Samuel M., Myburgh, Elmarie, Philipon, Cintia, Brown, Elaine, Meissner, Markus, Brewer, James, Mottram, Jeremy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913733/
https://www.ncbi.nlm.nih.gov/pubmed/26991545
http://dx.doi.org/10.1111/mmi.13375