Cargando…

An HPLC method with diode array detector for the simultaneous quantification of chloroquine and desethylchloroquine in plasma and whole blood samples from Plasmodium vivax patients in Vietnam, using quinine as an internal standard

A sensitive, simple method for quantification of chloroquine (CQ) and desethylchloroquine (MCQ) in whole blood and plasma from Plasmodium vivax patients has been developed using HPLC with diode array detection (DAD). Solid‐phase extraction on Isolute‐96‐CBA was employed to process 100 μL of plasma/w...

Descripción completa

Detalles Bibliográficos
Autores principales: Van Pham, Toi, Pham Nguyen, Phuong, Nguyen Duc Khanh, Tho, Nguyen Thanh Thuy, Nhien, Nguyen Thuy Nha, Ca, Pouplin, Thomas, Farrar, Jeremy, Thwaites, Guy E., Tran Tinh, Hien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913743/
https://www.ncbi.nlm.nih.gov/pubmed/26578224
http://dx.doi.org/10.1002/bmc.3657