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Testing small molecule analogues of the Acanthocheilonema viteae immunomodulator ES‐62 against clinically relevant allergens

ES‐62 is a glycoprotein secreted by the filarial nematode Acanthocheilonema viteae that protects against ovalbumin (OVA)‐induced airway hyper‐responsiveness in mice by virtue of covalently attached anti‐inflammatory phosphorylcholine (PC) residues. We have recently generated a library of small molec...

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Detalles Bibliográficos
Autores principales: Janicova, L., Rzepecka, J., Rodgers, D. T., Doonan, J., Bell, K. S., Lumb, F. E., Suckling, C. J., Harnett, M. M., Harnett, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913752/
https://www.ncbi.nlm.nih.gov/pubmed/27059010
http://dx.doi.org/10.1111/pim.12322