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Connexin 50 Regulates Surface Ball-and-Socket Structures and Fiber Cell Organization

PURPOSE: The roles of gap junction protein connexin 50 (Cx50) encoded by Gja8, during lens development are not fully understood. Connexin 50 knockout (KO) lenses have decreased proliferation of epithelial cells and altered fiber cell denucleation. We further investigated the mechanism for cellular d...

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Detalles Bibliográficos
Autores principales: Wang, Eddie, Geng, Andrew, Maniar, Ankur M., Mui, Byron W. H., Gong, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913802/
https://www.ncbi.nlm.nih.gov/pubmed/27281269
http://dx.doi.org/10.1167/iovs.16-19521