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The bacterial DnaA-trio replication origin element specifies ssDNA initiator binding

DNA replication is tightly controlled to ensure accurate inheritance of genetic information. In all organisms initiator proteins possessing AAA+ (ATPases associated with various cellular activities) domains bind replication origins to license new rounds of DNA synthesis1. In bacteria the master init...

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Detalles Bibliográficos
Autores principales: Richardson, Tomas T., Harran, Omar, Murray, Heath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913881/
https://www.ncbi.nlm.nih.gov/pubmed/27281207
http://dx.doi.org/10.1038/nature17962