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Heparanase Activates Antithrombin through the Binding to Its Heparin Binding Site

Heparanase is an endoglycosidase that participates in morphogenesis, tissue repair, heparan sulphates turnover and immune response processes. It is over-expressed in tumor cells favoring the metastasis as it penetrates the endothelial layer that lines blood vessels and facilitates the metastasis by...

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Detalles Bibliográficos
Autores principales: Bohdan, Nataliya, Espín, Salvador, Águila, Sonia, Teruel-Montoya, Raúl, Vicente, Vicente, Corral, Javier, Martínez-Martínez, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913942/
https://www.ncbi.nlm.nih.gov/pubmed/27322195
http://dx.doi.org/10.1371/journal.pone.0157834