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Differentiation of Induced Pluripotent Stem Cells to Lentoid Bodies Expressing a Lens Cell-Specific Fluorescent Reporter

Curative approaches for eye cataracts and other eye abnormalities, such as myopia and hyperopia currently suffer from a lack of appropriate models. Here, we present a new approach for in vitro growth of lentoid bodies from induced pluripotent stem (iPS) cells as a tool for ophthalmological research....

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Detalles Bibliográficos
Autores principales: Anand, Taruna, Talluri, Thirumala R., Kumar, Dharmendra, Garrels, Wiebke, Mukherjee, Ayan, Debowski, Katharina, Behr, Rüdiger, Kues, Wilfried A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913943/
https://www.ncbi.nlm.nih.gov/pubmed/27322380
http://dx.doi.org/10.1371/journal.pone.0157570