Amphiphilic core–shell nanoparticles containing dense polyethyleneimine shells for efficient delivery of microRNA to Kupffer cells

Efficient and targeted delivery approach to transfer exogenous genes into macrophages is still a great challenge. Current gene delivery methods often result in low cellular uptake efficiency in vivo in some types of cells, especially for the Kupffer cells (KCs). In this article, we demonstrate that...

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Detalles Bibliográficos
Autores principales: Liu, Zuojin, Niu, Dechao, Zhang, Junyong, Zhang, Wenfeng, Yao, Yuan, Li, Pei, Gong, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913979/
https://www.ncbi.nlm.nih.gov/pubmed/27366061
http://dx.doi.org/10.2147/IJN.S101251