DNA methylation in human epigenomes depends on local topology of CpG sites

In vertebrates, methylation of cytosine at CpG sequences is implicated in stable and heritable patterns of gene expression. The classical model for inheritance, in which individual CpG sites are independent, provides no explanation for the observed non-random patterns of methylation. We first invest...

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Detalles Bibliográficos
Autores principales: Lövkvist, Cecilia, Dodd, Ian B., Sneppen, Kim, Haerter, Jan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914085/
https://www.ncbi.nlm.nih.gov/pubmed/26932361
http://dx.doi.org/10.1093/nar/gkw124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914085/
https://www.ncbi.nlm.nih.gov/pubmed/26932361
http://dx.doi.org/10.1093/nar/gkw124

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