Promoter–enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase

PPARγ2 is a critical lineage-determining transcription factor that is essential for adipogenic differentiation. Here we report characterization of the three-dimensional structure of the PPARγ2 locus after the onset of adipogenic differentiation and the mechanisms by which it forms. We identified a d...

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Detalles Bibliográficos
Autores principales: LeBlanc, Scott E., Wu, Qiong, Lamba, Pallavi, Sif, Saïd, Imbalzano, Anthony N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914087/
https://www.ncbi.nlm.nih.gov/pubmed/26935580
http://dx.doi.org/10.1093/nar/gkw129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914087/
https://www.ncbi.nlm.nih.gov/pubmed/26935580
http://dx.doi.org/10.1093/nar/gkw129

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