Cargando…
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes
Ectopic expression of the double homeodomain transcription factor DUX4 causes facioscapulohumeral muscular dystrophy (FSHD). Mechanisms of action of DUX4 are currently unknown. Using immortalized human myoblasts with a titratable DUX4 transgene, we identify by mass spectrometry an interaction betwee...
Autores principales: | Choi, Si Ho, Gearhart, Micah D., Cui, Ziyou, Bosnakovski, Darko, Kim, Minjee, Schennum, Natalie, Kyba, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914088/ https://www.ncbi.nlm.nih.gov/pubmed/26951377 http://dx.doi.org/10.1093/nar/gkw141 |
Ejemplares similares
-
DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers
por: Li, Shanshan, et al.
Publicado: (2018) -
The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP
por: Wurm, Torsten, et al.
Publicado: (2012) -
The acetylation of transcription factor HBP1 by p300/CBP enhances p16(INK4A) expression
por: Wang, Weibin, et al.
Publicado: (2012) -
The LIM protein Ajuba recruits DBC1 and CBP/p300 to acetylate ERα and enhances ERα target gene expression in breast cancer cells
por: Xu, Beihui, et al.
Publicado: (2019) -
Genome-wide assessment of differential roles for p300 and CBP in transcription regulation
por: Ramos, Yolande F. M., et al.
Publicado: (2010)