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Nascent RNA length dictates opposing effects of NusA on antitermination

The NusA protein is a universally conserved bacterial transcription elongation factor that binds RNA polymerase (RNAP). When functioning independently, NusA enhances intrinsic termination. Paradoxically, NusA stimulates the function of the N and Q antiterminator proteins of bacteriophage λ. The mech...

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Detalles Bibliográficos
Autores principales: Wells, Christopher D., Deighan, Padraig, Brigham, MacKenzie, Hochschild, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914094/
https://www.ncbi.nlm.nih.gov/pubmed/27025650
http://dx.doi.org/10.1093/nar/gkw198