Coding exon-structure aware realigner (CESAR) utilizes genome alignments for accurate comparative gene annotation

Identifying coding genes is an essential step in genome annotation. Here, we utilize existing whole genome alignments to detect conserved coding exons and then map gene annotations from one genome to many aligned genomes. We show that genome alignments contain thousands of spurious frameshifts and s...

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Detalles Bibliográficos
Autores principales: Sharma, Virag, Elghafari, Anas, Hiller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914097/
https://www.ncbi.nlm.nih.gov/pubmed/27016733
http://dx.doi.org/10.1093/nar/gkw210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914097/
https://www.ncbi.nlm.nih.gov/pubmed/27016733
http://dx.doi.org/10.1093/nar/gkw210

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