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Coding exon-structure aware realigner (CESAR) utilizes genome alignments for accurate comparative gene annotation
Identifying coding genes is an essential step in genome annotation. Here, we utilize existing whole genome alignments to detect conserved coding exons and then map gene annotations from one genome to many aligned genomes. We show that genome alignments contain thousands of spurious frameshifts and s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914097/ https://www.ncbi.nlm.nih.gov/pubmed/27016733 http://dx.doi.org/10.1093/nar/gkw210 |