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The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans

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During ribosomal RNA (rRNA) maturation, cleavages at defined sites separate the mature rRNAs from spacer regions, but the identities of several enzymes required for 18S rRNA release remain unknown. PilT N-terminus (PIN) domain proteins are frequently endonucleases and the PIN domain protein Utp24 is...

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Detalles Bibliográficos
Autores principales:	Wells, Graeme R., Weichmann, Franziska, Colvin, David, Sloan, Katherine E., Kudla, Grzegorz, Tollervey, David, Watkins, Nicholas J., Schneider, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914098/ https://www.ncbi.nlm.nih.gov/pubmed/27034467 http://dx.doi.org/10.1093/nar/gkw213

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