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Structure and dynamics of DNA loops on nucleosomes studied with atomistic, microsecond-scale molecular dynamics

DNA loop formation on nucleosomes is strongly implicated in chromatin remodeling and occurs spontaneously in nucleosomes subjected to superhelical stress. The nature of such loops depends crucially on the balance between DNA deformation and DNA interaction with the nucleosome core. Currently, no hig...

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Detalles Bibliográficos
Autores principales: Pasi, Marco, Lavery, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914111/
https://www.ncbi.nlm.nih.gov/pubmed/27098037
http://dx.doi.org/10.1093/nar/gkw293