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Drug resistance in cancer: molecular evolution and compensatory proliferation

Targeted therapies have revolutionized cancer treatment. Unfortunately, their success is limited due to the development of drug resistance within the tumor, which is an evolutionary process. Understanding how drug resistance evolves is a prerequisite to a better success of targeted therapies. Resist...

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Detalles Bibliográficos
Autor principal: Friedman, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914245/
https://www.ncbi.nlm.nih.gov/pubmed/26909596
http://dx.doi.org/10.18632/oncotarget.7459