Severe chronic cerebral hypoperfusion induces microglial dysfunction leading to memory loss in APPswe/PS1 mice

Cerebral vasculature plays a key role in controlling brain homeostasis. Cerebral vasculature dysfunction, associated to irregularities in cerebral blood perfusion, has been proposed to directly contribute to Alzheimer's disease (AD) pathogenesis. More precisely, chronic cerebral hypoperfusion,...

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Detalles Bibliográficos
Autores principales: Bordeleau, Maude, ElAli, Ayman, Rivest, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914254/
https://www.ncbi.nlm.nih.gov/pubmed/26918610
http://dx.doi.org/10.18632/oncotarget.7689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914254/
https://www.ncbi.nlm.nih.gov/pubmed/26918610
http://dx.doi.org/10.18632/oncotarget.7689

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