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Ectopic mineralization of cartilage and collagen-rich tendons and ligaments in Enpp1(asj-2J) mice
Generalized arterial calcification of infancy (GACI), an autosomal recessive disorder caused by mutations in the ENPP1 gene, manifests with extensive mineralization of the cardiovascular system. A spontaneous asj-2J mutant mouse has been characterized as a model for GACI. Previous studies focused on...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914264/ https://www.ncbi.nlm.nih.gov/pubmed/26910915 http://dx.doi.org/10.18632/oncotarget.7455 |