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Ectopic mineralization of cartilage and collagen-rich tendons and ligaments in Enpp1(asj-2J) mice

Generalized arterial calcification of infancy (GACI), an autosomal recessive disorder caused by mutations in the ENPP1 gene, manifests with extensive mineralization of the cardiovascular system. A spontaneous asj-2J mutant mouse has been characterized as a model for GACI. Previous studies focused on...

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Detalles Bibliográficos
Autores principales: Zhang, Jieyu, Dyment, Nathaniel A., Rowe, David W., Siu, Sarah Y., Sundberg, John P., Uitto, Jouni, Li, Qiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914264/
https://www.ncbi.nlm.nih.gov/pubmed/26910915
http://dx.doi.org/10.18632/oncotarget.7455