CD226 reduces endothelial cell glucose uptake under hyperglycemic conditions with inflammation in type 2 diabetes mellitus

CD226 is a co-stimulatory adhesion molecule found on immune and endothelial cells. Here, we evaluated a possible role for CD226 in inhibiting glucose uptake in isolated human umbilical vein endothelial cells (HUVECs) and in wild-type (WT) and CD226 knockout (KO) mice with high-fat diet (HFD)-induced...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Liu, Tian, Chen, Yu, Dong, Zilong, Zhang, Jinxue, Sun, Yizheng, Jin, Boquan, Gao, Feng, Guo, Shuzhong, Zhuang, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914265/
https://www.ncbi.nlm.nih.gov/pubmed/26910838
http://dx.doi.org/10.18632/oncotarget.7505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914265/
https://www.ncbi.nlm.nih.gov/pubmed/26910838
http://dx.doi.org/10.18632/oncotarget.7505

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