REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling

Prion diseases are a group of infectious neurodegenerative diseases characterized by multiple neuropathological hallmarks including synaptic damage, spongiform degeneration and neuronal death. The factors and mechanisms that maintain cellular morphological integrity and protect against neurodegenera...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Zhiqi, Zhu, Ting, Zhou, Xiangmei, Barrow, Paul, Yang, Wei, Cui, Yongyong, Yang, Lifeng, Zhao, Deming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914267/
https://www.ncbi.nlm.nih.gov/pubmed/26919115
http://dx.doi.org/10.18632/oncotarget.7640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914267/
https://www.ncbi.nlm.nih.gov/pubmed/26919115
http://dx.doi.org/10.18632/oncotarget.7640

Ejemplares similares