Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7

Naïve FoxP3-expressing regulatory T-cells (Tregs) are essential to control immune responses via continuous replenishment of the activated-Treg pool with thymus-committed suppressor cells. The mechanisms underlying naïve-Treg maintenance throughout life in face of the age-associated thymic involution...

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Detalles Bibliográficos
Autores principales: Silva, Susana L., Albuquerque, Adriana S., Serra-Caetano, Ana, Foxall, Russell B., Pires, Ana R., Matoso, Paula, Fernandes, Susana M., Ferreira, João, Cheynier, Rémi, Victorino, Rui M. M., Caramalho, Iris, Barata, João T., Sousa, Ana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914276/
https://www.ncbi.nlm.nih.gov/pubmed/26910841
http://dx.doi.org/10.18632/oncotarget.7512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914276/
https://www.ncbi.nlm.nih.gov/pubmed/26910841
http://dx.doi.org/10.18632/oncotarget.7512

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