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Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival

Upregulation of SESTRIN 2 (SESN2) has been reported in response to diverse cellular stresses. In this study we demonstrate SESTRIN 2 induction following endoplasmic reticulum (ER) stress. ER stress-induced increases in SESTRIN 2 expression were dependent on both PERK and IRE1/XBP1 arms of the unfold...

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Detalles Bibliográficos
Autores principales: Saveljeva, Svetlana, Cleary, Patricia, Mnich, Katarzyna, Ayo, Abiodun, Pakos-Zebrucka, Karolina, Patterson, John B, Logue, Susan E., Samali, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914282/
https://www.ncbi.nlm.nih.gov/pubmed/26930721
http://dx.doi.org/10.18632/oncotarget.7601