Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells’ sensitivity to paclitaxel

The molecular pathways that contribute to the proliferation and drug response of cancer cells are highly complex and currently insufficiently characterized. We have identified a previously unknown microRNA-based mechanism that provides cancer cells means to stimulate tumorigenesis via increased geno...

Descripción completa

Detalles Bibliográficos
Autores principales: Tambe, Mahesh, Pruikkonen, Sofia, Mäki-Jouppila, Jenni, Chen, Ping, Elgaaen, Bente Vilming, Straume, Anne Hege, Huhtinen, Kaisa, Cárpen, Olli, Lønning, Per Eystein, Davidson, Ben, Hautaniemi, Sampsa, Kallio, Marko J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Chromosome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914283/
https://www.ncbi.nlm.nih.gov/pubmed/26943585
http://dx.doi.org/10.18632/oncotarget.7860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914283/
https://www.ncbi.nlm.nih.gov/pubmed/26943585
http://dx.doi.org/10.18632/oncotarget.7860

Ejemplares similares