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CRISPR/Cas9 and cancer targets: future possibilities and present challenges
All cancers have multiple mutations that can largely be grouped into certain classes depending on the function of the gene in which they lie and these include oncogenic changes that enhance cellular proliferation, loss of function of tumor suppressors that regulate cell growth potential and inductio...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914286/ https://www.ncbi.nlm.nih.gov/pubmed/26840090 http://dx.doi.org/10.18632/oncotarget.7104 |