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CRISPR/Cas9 and cancer targets: future possibilities and present challenges

All cancers have multiple mutations that can largely be grouped into certain classes depending on the function of the gene in which they lie and these include oncogenic changes that enhance cellular proliferation, loss of function of tumor suppressors that regulate cell growth potential and inductio...

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Detalles Bibliográficos
Autores principales: White, Martyn K., Khalili, Kamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914286/
https://www.ncbi.nlm.nih.gov/pubmed/26840090
http://dx.doi.org/10.18632/oncotarget.7104