Intercellular transfer of small RNAs from astrocytes to lung tumor cells induces resistance to chemotherapy

Brain metastases are resistant to chemotherapy and carry a poor prognosis. Studies have shown that tumor cells are surrounded by activated astrocytes, whose cytoprotective properties they exploit for protection from chemotherapy-induced apoptosis. The mechanism of such astrocytic protection is poorl...

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Detalles Bibliográficos
Autores principales: Menachem, Assaf, Makovski, Victoria, Bodner, Or, Pasmanik-Chor, Metsada, Stein, Reuven, Shomron, Noam, Kloog, Yoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914300/
https://www.ncbi.nlm.nih.gov/pubmed/26871466
http://dx.doi.org/10.18632/oncotarget.7273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914300/
https://www.ncbi.nlm.nih.gov/pubmed/26871466
http://dx.doi.org/10.18632/oncotarget.7273

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