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Intercellular transfer of small RNAs from astrocytes to lung tumor cells induces resistance to chemotherapy

Brain metastases are resistant to chemotherapy and carry a poor prognosis. Studies have shown that tumor cells are surrounded by activated astrocytes, whose cytoprotective properties they exploit for protection from chemotherapy-induced apoptosis. The mechanism of such astrocytic protection is poorl...

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Detalles Bibliográficos
Autores principales:	Menachem, Assaf, Makovski, Victoria, Bodner, Or, Pasmanik-Chor, Metsada, Stein, Reuven, Shomron, Noam, Kloog, Yoel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914300/ https://www.ncbi.nlm.nih.gov/pubmed/26871466 http://dx.doi.org/10.18632/oncotarget.7273

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