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Mutant p53 protects ETS2 from non-canonical COP1/DET1 dependent degradation

Mutations in the tumor suppressor gene TP53 contribute to the development of approximately half of all human cancers. One mechanism by which mutant p53 (mtp53) acts is through interaction with other transcription factors, which can either enhance or repress the transcription of their target genes. M...

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Detalles Bibliográficos
Autores principales: Carrero, Zunamys I., Kollareddy, Madhusudhan, Chauhan, Krishna M., Ramakrishnan, Gopalakrishnan, Martinez, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914304/
https://www.ncbi.nlm.nih.gov/pubmed/26871468
http://dx.doi.org/10.18632/oncotarget.7275