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Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction
Glioblastomas are resistant to many kinds of treatment, including chemotherapy, radiation and other adjuvant therapies. As(2)O(3) reportedly induces ROS generation in cells, suggesting it may be able to induce telomerase suppression and telomere dysfunction in glioblastoma cells. We show here that A...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914314/ https://www.ncbi.nlm.nih.gov/pubmed/26871293 http://dx.doi.org/10.18632/oncotarget.7259 |