Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction

Glioblastomas are resistant to many kinds of treatment, including chemotherapy, radiation and other adjuvant therapies. As(2)O(3) reportedly induces ROS generation in cells, suggesting it may be able to induce telomerase suppression and telomere dysfunction in glioblastoma cells. We show here that A...

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Detalles Bibliográficos
Autores principales: Cheng, Ye, Li, Yunqian, Ma, Chengyuan, Song, Yang, Xu, Haiyang, Yu, Hongquan, Xu, Songbai, Mu, Qingchun, Li, Haisong, Chen, Yong, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914314/
https://www.ncbi.nlm.nih.gov/pubmed/26871293
http://dx.doi.org/10.18632/oncotarget.7259

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