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Regression/Eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide
Malignant gliomas have poor prognosis and urgently require new therapies. Activating Transcription Factor 5 (ATF5) is highly expressed in gliomas, and interference with its expression/function precipitates targeted glioma cell apoptosis in vitro and in vivo. We designed a novel deliverable truncated...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914317/ https://www.ncbi.nlm.nih.gov/pubmed/26863637 http://dx.doi.org/10.18632/oncotarget.7212 |