High Mobility Group A2 protects cancer cells against telomere dysfunction

The non-histone chromatin binding protein High Mobility Group AT-hook protein 2 (HMGA2) plays important roles in the repair and protection of genomic DNA in embryonic stem cells and cancer cells. Here we show that HMGA2 localizes to mammalian telomeres and enhances telomere stability in cancer cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Natarajan, Suchitra, Begum, Farhana, Gim, Jeonga, Wark, Landon, Henderson, Dana, Davie, James R., Hombach-Klonisch, Sabine, Klonisch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914320/
https://www.ncbi.nlm.nih.gov/pubmed/26799419
http://dx.doi.org/10.18632/oncotarget.6938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914320/
https://www.ncbi.nlm.nih.gov/pubmed/26799419
http://dx.doi.org/10.18632/oncotarget.6938

Ejemplares similares