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Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model

A patient with high grade undifferentiated pleomorphic soft-tissue sarcoma from a striated muscle was grown orthotopically in the right biceps femoris muscle of mice to establish a patient-derived orthotopic xenograft (PDOX) model. Twenty PDOX mice were divided into 4 groups: G1, control without tre...

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Detalles Bibliográficos
Autores principales: Murakami, Takashi, DeLong, Jonathan, Eilber, Fritz C., Zhao, Ming, Zhang, Yong, Zhang, Nan, Singh, Arun, Russell, Tara, Deng, Samantha, Reynoso, Jose, Quan, Cuong, Hiroshima, Yukihiko, Matsuyama, Ryusei, Chishima, Takashi, Tanaka, Kuniya, Bouvet, Michael, Chawla, Sant, Endo, Itaru, Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914321/
https://www.ncbi.nlm.nih.gov/pubmed/26859573
http://dx.doi.org/10.18632/oncotarget.7226