Cargando…
Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo
It remains a challenge in oncology to identify novel drug regimens to efficiently tackle glioblastoma, the most common primary brain tumor in adults. Here, we target deubiquitinases for glioblastoma therapy by utilizing the small-molecule inhibitor WP1130 which has been characterized as a deubiquiti...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914322/ https://www.ncbi.nlm.nih.gov/pubmed/26872380 http://dx.doi.org/10.18632/oncotarget.7302 |