SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer

Sterol regulatory element-binding protein-2 (SREBP-2) transcription factor mainly controls cholesterol biosynthesis and homeostasis in normal cells. The role of SREBP-2 in lethal prostate cancer (PCa) progression remains to be elucidated. Here, we showed that expression of SREBP-2 was elevated in ad...

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Detalles Bibliográficos
Autores principales: Li, Xiangyan, Wu, Jason Boyang, Li, Qinlong, Shigemura, Katsumi, Chung, Leland W.K., Huang, Wen-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914327/
https://www.ncbi.nlm.nih.gov/pubmed/26883200
http://dx.doi.org/10.18632/oncotarget.7331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914327/
https://www.ncbi.nlm.nih.gov/pubmed/26883200
http://dx.doi.org/10.18632/oncotarget.7331

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