Combination Chemotherapy with Suboptimal Doses of Benznidazole and Pentoxifylline Sustains Partial Reversion of Experimental Chagas' Heart Disease

Chronic chagasic cardiomyopathy (CCC) progresses with parasite persistence, fibrosis, and electrical alterations associated with an unbalanced immune response such as high plasma levels of tumor necrosis factor (TNF) and nitric oxide (NO). Presently, the available treatments only mitigate the sympto...

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Detalles Bibliográficos
Autores principales: Vilar-Pereira, Glaucia, Resende Pereira, Isabela, de Souza Ruivo, Leonardo Alexandre, Cruz Moreira, Otacilio, da Silva, Andrea Alice, Britto, Constança, Lannes-Vieira, Joseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914640/
https://www.ncbi.nlm.nih.gov/pubmed/27161638
http://dx.doi.org/10.1128/AAC.02123-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914640/
https://www.ncbi.nlm.nih.gov/pubmed/27161638
http://dx.doi.org/10.1128/AAC.02123-15

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